Organometallic Compounds
Medchemexpress LLC NH-bis(PEG3-Boc) | 1814901-03-5 | 98.0% | C26H51NO10 | 1 G
NH-bis(PEG3-Boc) is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are compounds designed with two distinct ligands connected by a linker: one ligand binds to an E3 ubiquitin ligase, and the other targets a specific protein. This mechanism exploits the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins. This product appears as a colorless to light yellow liquid.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates selective degradation of target proteins
- Colorless to light yellow liquid
Medchemexpress LLC m-PEG3-CH2CH2COOH | 67319-28-2 | MFCD11041124 | 97.0% | 236.26 g·mol⁻¹ | C10H20O6 | 5 G
m-PEG3-CH2CH2COOH is a methoxy-terminated PEG3 carboxylic acid used as a short, flexible spacer for bioconjugation chemistry. It is employed as a non-cleavable linker in antibody-drug conjugate (ADC) assembly and as a PEG-based linker in PROTAC and other conjugation workflows, providing a terminal carboxylic acid for coupling reactions and improving solubility of conjugates.
- Methoxy-terminated PEG3 spacer providing flexibility.
- Terminal carboxylic acid suitable for amide coupling and esterification.
- Molecular weight 236.26 g·mol⁻¹ for predictable spacer length.
- High purity (approximately 97.0%) suitable for research applications.
- Available in small research-scale quantities and recommended refrigerated storage for stability.
Medchemexpress LLC BM-PEG3 | 86099-06-1 | 98.0% | 100 MG
BM-PEG3 is a polyethylene glycol (PEG)-based PROTAC linker designed for the synthesis of PROTACs. PROTACs (Proteolysis Targeting Chimeras) are compounds that utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins. They function by connecting two different ligands, one for an E3 ubiquitin ligase and another for the target protein, enabling targeted degradation.
- PEG-based PROTAC linker
- For research use only
- Purity: 98.0%
- Molecular weight: 352.34
- Molecular formula: C16H20N2O7
- Appearance: White to light yellow solid
- Storage as powder: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 6 months, -20°C for 1 month
- Solubility in DMSO: 100 mg/mL (in vitro)
- Solubility in 10% DMSO, 90% corn oil: ≥ 2.5 mg/mL (in vivo)
Medchemexpress LLC Fmoc-NH-PEG3-CH2CH2COOH | 867062-95-1 | 99.8% | 443.49 g/mol | C24H29NO7 | 5 G
Fmoc-NH-PEG3-CH2CH2COOH is an Fmoc-protected PEG3-based cleavable linker used for conjugation chemistry in research applications such as antibody-drug conjugates and PROTAC synthesis. It provides a short PEG spacer with an Fmoc-protected amino terminus and a terminal carboxylic acid for coupling reactions.
- High purity suitable for research use.
- PEG3 spacer provides solubility and flexibility.
- Fmoc protection enables standard amine deprotection workflows.
- Terminal carboxylic acid allows amide bond formation.
- Available in multiple pack sizes for synthesis scale-up.
![Medchemexpress LLC 2-[2-(2-trityloxyethoxy)ethoxy]ethanol | 133699-09-9 | 99.6% | 392.49 g/mol | C25H28O4 | 5 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202768.png-250.jpg)
Medchemexpress LLC 2-[2-(2-trityloxyethoxy)ethoxy]ethanol | 133699-09-9 | 99.6% | 392.49 g/mol | C25H28O4 | 5 G
Tr-PEG3-OH is a non-cleavable, three-unit polyethylene glycol (PEG) linker intended for research use in the synthesis of antibody-drug conjugates (ADCs). It provides a short hydrophilic spacer that improves solubility and linker flexibility while remaining stable under biological conditions.
- Non-cleavable 3-unit polyethylene glycol linker suitable for ADC construction.
- Improves solubility and hydrophilicity of conjugates.
- Short PEG spacer reduces steric hindrance between antibody and payload.
- High purity supports reproducible conjugation chemistry.
- Defined molecular weight for consistent analytical characterization.
Medchemexpress LLC THP-PEG3-OH | 60221-37-6 | 98.7% | 1 G
THP-PEG3-OH is a PEG-based PROTAC linker used in the synthesis of PROTACs. This compound is intended for research use only and is not sold to patients.
- Enables the synthesis of PROTACs
- Functions as a PROTAC linker
- Utilizes the PROTAC pathway
- Facilitates selective degradation of target proteins via the ubiquitin-proteasome system
Medchemexpress LLC Zinc gluconate | 4468-02-4 | MFCD00868110 | 98.0% | 455.67 | C12H22O14Zn | 25 G
Zinc gluconate is the zinc salt of gluconic acid provided as a white powder for research and analytical use. It serves as a source of bioavailable zinc ions for biochemical, pharmacological, and nutritional studies, and is supplied with supporting documentation for laboratory handling.
- High purity (98.0%) for research-grade applications.
- Anhydrous molecular weight 455.67 and formula C12H22O14Zn.
- Soluble in DMSO and water at 50 mg/mL with sonication.
- Supplied as a dry powder; store sealed at 4°C to protect from moisture.
- Datasheet and certificate of analysis available for lot-specific data.
- Suitable for biochemical, pharmacological, and nutritional research.
Medchemexpress LLC S -2- 2- tert-Buto 50g
(S)-2-(2-((tert-Butoxycarbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid (Boc-his(trt)-aib-ohol) is a drug intermediate for synthesis of various active compounds
eMolecules Oakwood Chemical 1-Methoxy-1-trimethylsilyloxypropene 250mg 537724921 S11001 0 000 34880-70-1 MFCD00671554 160 288 C7H16O2Si
Oakwood Chemical 1-Methoxy-1-trimethylsilyloxypropene 250mg 537724921 S11001 0 000 34880-70-1 MFCD00671554 160 288 C7H16O2Si
eMolecules Chem-Impex Triisopropylsilyl chloride 1kg 603112652 36410 0 000 13154-24-0 MFCD00009656 192 800 C9H21ClSi
Chem-Impex Triisopropylsilyl chloride 1kg 603112652 36410 0 000 13154-24-0 MFCD00009656 192 800 C9H21ClSi
amino]-3-methylbutanoic acid | 45170-31-8 | 98.0% | 231.29 | 25 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000402904-logo.png-250.jpg){kind=logo}
Medchemexpress LLC (2S)-2-[[(tert-Butoxy)carbonyl](methyl)amino]-3-methylbutanoic acid | 45170-31-8 | 98.0% | 231.29 | 25 G
(2S)-2-[[(tert-Butoxy)carbonyl](methyl)amino]-3-methylbutanoic acid is a valine derivative intended for research use only. Amino acids and their derivatives, such as this product, are commercially utilized as ergogenic supplements.
- Influences the secretion of anabolic hormones
- Supplies fuel during exercise
- Improves mental performance during stress-related tasks
- Helps prevent exercise-induced muscle damage
- Recognized as a beneficial ergogenic dietary substance